Cyclopamine, CAS 4449-51-8

Hedgehog signaling blocker

Product Type: Inhibitor

CAS No.: 4449-51-8

MolecularFormula: C27H41NO2

Molecular Weight: 434,15

Source: Synthetic

Purity: >98%

Solubility: Soluble to 5 mM in ethanol

Appearance: White Solid

PubChem CID: 442972

Scientific Background: Cyclopamine is a hedgehog signaling pathway inhibitor that influences the balance between the active and inactive forms of the Smoothened protein (1). It is being investigated as a treatment agent in basal cell carcinoma, medulloblastoma and rhabdomyosarcoma (1, 2).

References: 1. Beachy P.A., et al. (2000) Nature. 406(6799): 1005-1009.2. Yauch R.L., et al. (2009) Science. 326(5952): 572-574.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-226-1MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-226-1MG
• Package Unit: 1 mg
• Quantity Unit: STK