Application Note: WB: 1:500-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 58
Form: Liquid
Buffer (with preservative): PBS, 50% Glycerol, 0.02% Sodium azide.
Concentration: batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010]
Uniprot ID: P22680
Antigen Species: Human
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human CYP7A1 (NP_000771.2).
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: cytochrome P450 family 7 subfamily A member 1
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