Cytochalasin D, CAS 22144-77-0

Actin polymerization inhibitor

Product Type: Inhibitor

CAS No.: 22144-77-0

MolecularFormula: C30H37NO6

Molecular Weight: 507,63

Source: Synthetic

Purity: >98% (TLC); NMR (Conforms)

Solubility: Soluble to 10 mM in ethanol and to 50 mM in DMSO

Appearance: White Solid

PubChem CID: 5458428

Scientific Background: Cytochalasins have the ability to bind to actin filaments and block polymerization and elongation of actin. As a result, they can change cellular morphology, inhibit cellular processes and cause cells to undergo apoptosis (1). Cytochalasin D in particular can inhibit protein synthesis (2).

References: 1.  Haidle A., and Myers A. (2004) Proc Natl Acad Sci. 101(33): 12048-12053.2. Ornelles et al., (1986) Mol Cell Biol. 6(5): 1650-1662.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-241-5MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-241-5MG
• Package Unit: 5 mg
• Quantity Unit: STK
• Reactivity: Human, Various species