Formulation: A powder
Formal Name: 8-hydroxy-3-(hydroxymethyl)-6-methoxy-1H-2-benzopyran-1-one
Purity: ≥98%
Formula Markup: C11H10O5
Formula Weight: 222,2
Shelf life (days): 365
CAS Number: 132971-59-6
Notes: Cytogenin is a coumarin derivative originally found in S. eurocidicum that has diverse biological activities.{72159,72160} It reduces tumor weight in an Ehrlich murine spontaneous adenocarcinoma model when administered at a dose of 25 mg/kg per day.{72159} In vivo, cytogenin (30 and 100 mg/kg per day) reduces streptozotocin-induced decreases in body weight and increases in plasma glucose levels and macrophage pancreatic infiltration in a mouse model of diabetes.{72160} It also decreases zymosan- and LPS-induced nitric oxide production, as well as LPS-induced increases in Il-6 levels, in isolated mouse macrophages after administration at a dose of 100 mg/kg per day.
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