Clone Name: RM226
Application Note: WB: 1:1000. IHC-P: 1:100 - 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 62
Specificity/Sensitivity: This antibody reacts to human CK-5 (Cytokeratin 5), and does not cross-react to CK-6 (Cytokeratin 6).
Form: Liquid
Buffer (with preservative): PBS, 1% BSA, 50% Glycerol, 0.09% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Uniprot ID: P13647
Antigen Species: Human
Immunogen: A peptide corresponding to the C-terminus of Human Cytokeratin 5
Purification: Protein A purified
Conjugation: Unconjugated
Full Name: keratin 5