D-Proline, 4-hydroxy-, methyl ester (hydrochloride), CAS 114676-59-4

Product Description: D-Proline, 4-hydroxy-, methyl ester hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). D-Proline, 4-hydroxy-, methyl ester hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2

Applications: Cancer-programmed cell death

Formula: C6H12ClNO3

References: [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985./[2]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.

CAS Number: 114676-59-4

Molecular Weight: 181.62

Compound Purity: 98.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker;PROTAC Linkers

• SKU: MEXHY-76105-25G
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-76105-25G
• Package Unit: 25 g
• Quantity Unit: STK