Dabcyl-K-SARS-CoV-2 Replicase Polyprotein 1ab (3235-3246)-E-EDANS (trifluoroacetate salt)

Formulation: A solid

Formal Name: N2-[4-[[4-(dimethylamino)phenyl]azo]benzoyl]-L-lysyl-L-threonyl-L-seryl-L-alanyl-L-valyl-L-leucyl-L-glutaminyl-L-serylglycyl-L-phenylalanyl-L-arginyl-L-lysyl-L-methionyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-α-glutamine, trifluoroacetate salt

Purity: ≥90%

Formula Markup: C95H141N25O24S2 • XCF3COOH

Formula Weight: 2081,4

Shelf life (days): 1460

Notes: Dabcyl-K-SARS-CoV-2 replicase polyprotein 1ab (pp1ab) (3235-3246)-E-EDANS is a fluorogenic substrate for severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 main protease (Mpro), also known as 3C-like protease (3CLpro).{67505,67508} Upon enzymatic cleavage by SARS-CoV or SARS-CoV-2 Mpro at the Gln-Ser site, EDANS is separated from the Dabcyl quencher and its fluorescence can be used to quantify SARS-CoV or SARS-CoV-2 Mpro activity.{67505,67508,55436} EDANS displays excitation/emission maxima of 340/485 nm, respectively.

• SKU: CAY37409-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37409-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK
• Application: Fluorescence