DBCO-NHCO-S-S-NHS ester

Product Description: DBCO-NHCO-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHCO-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C28H27N3O6S2

References: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Weight: 565.66

Compound Purity: 95.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: ADC Linker

• SKU: MEXHY-133412-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-133412-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK