DBCO-NHS ester 2, CAS 1384870-47-6

Product Description: DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Applications: Neuroscience-Neuromodulation

Formula: C25H22N2O5

References: [1]Tang F, et al. Chemoenzymatic synthesis of glycoengineered IgG antibodies and glycosite-specific antibody-drug conjugates. Nat Protoc. 2017 Aug;12(8):1702-1721.

CAS Number: 1384870-47-6

Molecular Weight: 430.45

Compound Purity: 99.69

Research Area: Cancer

Solubility: DMSO : 14.29 mg/mL (ultrasonic)

Target: ADC Linker

• SKU: MEXHY-115524-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-115524-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK