DBCO-PEG4-VC-PAB-DMEA-PNU-159682, CAS 2259318-56-2

Product Description: DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a agent-linker conjugate for ADC, consists the ADC linker DBCO-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682. DBCO-PEG4-VC-PAB-DMEA-PNU-159682 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Applications: Cancer-programmed cell death

Formula: C86H106N10O26

References: [1]John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1

CAS Number: 2259318-56-2

Molecular Weight: 1695.81

Compound Purity: 84.45

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Drug-Linker Conjugates for ADC

• SKU: MEXHY-126691-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-126691-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK