Product Description: DC41 is a DC1 derivative. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer[1][2].
Applications: Cancer-programmed cell death
Formula: C37H34ClN5O4S
References: [1]Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82./[2]Kovtun YV, et al. Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen. Cancer Res. 2006 Mar 15;66(6):3214-21.
CAS Number: 1354787-69-1
Molecular Weight: 680.21
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: ADC Cytotoxin