Decitabine, CAS 2353-33-5

DNA hypomethylation agent

Product Type: Inhibitor

CAS No.: 2353-33-5

MolecularFormula: C8H12N4O4

Molecular Weight: 228,2

Source: Synthetic

Purity: >98% (TLC), NMR conforms

Solubility: Soluble in 25 mg/ml DMSO, 11 mg/ml Water or Ethanol

Appearance: White Solid

PubChem CID: 451668

Scientific Background: Inhibits DNA methyltransferase. Induces demethylation and reactivation of silenced genes. Increases stem cell reprogramming efficiency. Stimulates osteogenic differentiation of human bone marrow stromal cells. Antitumor agent. Cell permeable.

References: 1. Bender C.M., et al. (1998) Cancer Res. 58: 95.2. El-Serafi A.T., et al. (2011) Differentiation 81: 35.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-352-50MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-352-50MG
• Package Unit: 50 mg
• Quantity Unit: STK