Deferitrin, CAS 239101-33-8

Formulation: A solid

Formal Name: (4S)-2-(2,4-dihydroxyphenyl)-4,5-dihydro-4-methyl-4-thiazolecarboxylic acid

Purity: ≥98%

Formula Markup: C11H11NO4S

Formula Weight: 253,3

Shelf life (days): 1460

CAS Number: 239101-33-8

Notes: Deferitrin is an iron chelator and a derivative of desferrithiocin that binds iron in a 2:1 (ligand:iron) ratio.{69152,69153} It inhibits the proliferation of L1210 murine leukemia cells (IC50 = 17 µM).{69154} Deferitrin (150 µmol/kg) induces iron excretion in iron-overloaded C. apella monkeys and beagle dogs with an iron clearing efficiency (ICE) of 14.5 and 9.3%, respectively.{69153} It reduces fecal and urine iron levels by 607 and 357 µg/kg in C. apella monkeys and beagle dogs, respectively.

• SKU: CAY33328-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 33328-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK
• Application: Reinstoffe