Deguelin, CAS 522-17-8

Akt inhibitor

Product Type: Inducer

CAS No.: 522-17-8

MolecularFormula: C23H22O6

Molecular Weight: 394,42

Source: Synthetic

Purity: >98%

Solubility: Soluble to 50 mM in ethanol and to 100 mM in DMSO

Appearance: Cream Solid

PubChem CID: 107935

Scientific Background: Deguelin is a rotenoid, and a naturally occurring insecticide. Deguelin displays anti-cancer activity by inhibiting the growth of pre-cancerous and cancerous cells (1). High doses may have negative effects on the heart, lungs and nerves however. Deguelin has also been shown to have a correlation with Parkinson's disease in rats (2).

References: 1. Lee H.Y. (2004) Biochem Pharmacol. 68(6): 1119-1124.2. Caboni P., et al. (2004) Chem Res. Toxicol. 17(11): 1540-1548.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-251-10MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-251-10MG
• Package Unit: 10 mg
• Quantity Unit: STK