Derazantinib, CAS 1234356-69-4

Description: Derazantinib (ARQ-087) is a potent, ATP-competitive, orally active tyrosine kinase inhibitor with IC50 values ​​of 4.5/1.8/4.35/3.4 nM for chondrocyte FGFR1/FGFR2/FGFR3/FGFR4, respectively.

CAS Number: 1234356-69-4

Formula: C29H29FN4O

Molecular Weight: 468,57

References: Balek L, et al. ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFRBone. 2017 Dec;105:57-66.

• SKU: TGMTQ0228-200mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: TQ0228-200mg
• Package Unit: 200 mg
• Quantity Unit: STK