Clone Name: AT19F2
Light Chain: Kappa
Application Note: WB: Recommended starting dilution is 1:3000.. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 27
Form: Liquid
Buffer (with preservative): PBS, 10% Glycerol, 0.02% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Uniprot ID: Q9NR28
Antigen Species: Human
Immunogen: The clone AT19F2 is derived from hybridization of mouse F2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SMAC/Diablo protein.
Purification: Protein A Purified
Conjugation: Unconjugated
Full Name: diablo IAP-binding mitochondrial protein
English
Deutsch
