Two autoimmune thyroid disorders are Graves' disease and Hashimoto's thyroiditis. In Hashimoto's thyroiditis cell and tissue-degrading reactions and an atrophic-induced hypofunction of the thyroid gland are typical, in Graves' disease the thyroid gland is enlarged and the proliferation rate and hormone synthesis are increased.
Triggers for type I diabetes are antibodies to insulin-producing pancreatic cells.