Formulation: A solid
Formal Name: N,N-dimethyl-α-[2-(1-naphthalenyloxy)ethyl]-benzenemethanamine, monohydrochloride
Purity: ≥98%
Formula Markup: C21H23NO • HCl
Formula Weight: 341,9
Shelf life (days): 1460
CAS Number: 1071929-03-7
Notes: DL-Dapoxetine is a racemic mixture of the serotonin (5-HT) reuptake inhibitors (R)-dapoxetine and (S)-dapoxetine.{65666} (S)-Dapoxetine is more potent than (R)-dapoxetine in a serotonin reuptake assay using isolated rat cerebral cortex membranes (IC50s = 10 and 35 nM, respectively).{65667} (S)-Dapoxetine also inhibits the reuptake of norepinephrine and dopamine in cells expressing the human transporters (IC50s = 202 and 1,720 nM, respectively).{65668} Formulations containing (S)-dapoxetine have been used in the treatment of premature ejaculation.