Product Description: DMBA-SIL-Mal-MMAE is a cytotoxin-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked DMBA-SIL-Mal[1].
Applications: Cancer-programmed cell death
Formula: C72H106N8O20
References: [1]Jeremy M Quintana, et al. Radiation Cleaved Drug-Conjugate Linkers Enable Local Payload Release. Bioconjug Chem. 2022 Aug 17;33(8):1474-1484.
CAS Number: 2923885-49-6
Molecular Weight: 1403.65
Compound Purity: 99.79
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Drug-Linker Conjugates for ADC