Formulation: A solid
Formal Name: 3-(2-naphthalenyl)-1-(3-pyridinyl)-2-propen-1-one
Purity: ≥98%
Formula Markup: C18H13NO
Formula Weight: 259,3
Shelf life (days): 1460
CAS Number: 1031063-36-1
Notes: DMU2105 is an inhibitor of the cytochrome P450 (CYP) isoform CYP1B1 (IC50 = 0.01 µM).{72079} It is selective for CYP1B1 over CYP1A1, CYP1A2, CYP3A4, and CYP2D6 (IC50s = 0.742, 1.2, 18, and 10 µM, respectively). DMU2105 enhances cisplatin-induced cell death in HEK293 cells overexpressing CYP1B1.