Dnase1Polyclonal Antibody, Rabbit

Abbreviation: DnaseⅠ

Target Synonym: Deoxyribonuclease-1; DNASE1; DNL1; DRNI

Conjugation: Unconjugated

UNIProt ID: P24855

Background: Deoxyribonuclease I (DNase I) is an endonuclease which is secreted to cleave DNA in the extracellular space down to an average of tetranucleotides with 5′ monophosphate and 3′ hydroxyl DNA ends . Both single-stranded DNA and double-stranded DNA are degraded by Dnase I. This nuclease appears to account for the major nucleolytic activity on DNA in serum and is responsible for the degradation of the majority of circulating DNA derived from apoptotic and necrotic cell death and from neutrophil extracellular traps. In addition to its role in the serum, it has been proposed as one of the deoxyribonucleases responsible for DNA fragmentation in the process of apoptosis.

Concentration: 0.7mg/mL

Immunogen: Recombinant Human DnaseⅠ protein expressed by E.coli.

Dilution: WB: 1:1000-2000

• SKU: ELSE-AB-40592-50
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-40592-50
• Package Unit: 50 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Western Blotting
• Host: Rabbit