Products from BPS Bioscience require a minimum order value above 400€Encompassing Amino Acids: 1-913 (end)
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Description: Human DNMT3a (GenBank Accession No. NM_175629), full length with N-terminal GST-tag, MW=128 kDa, expressed in a baculovirus-infected Sf9 cell expression system.
Format: Aqueous buffer solution
Formulation: 45 mM Tris-HCl, pH 8.0,124 mM NaCl, 2.4 mM KCl, 3 mM DTT, 18mM glutathione, and 10% glycerol.
Genbank: NM_175629
Host Cell Line: Sf9 cells
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal GST-tag
Uniprot: Q9Y6K1
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Shikauchi, Y. et al., Mol. Cell. Biol. 29 (7):1944-1958 (2009).
2. Zhao, Q. et al., Nat. Struct. Mol. Biol. 16 (3):304-311 (2009).Application Reference(s):
DNA 5-methylcytosine demethylation activities of the mammalian DNA methyltransferases (2013)
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