DOSEH (chloride)

Formulation: A solid

Formal Name: (2-hydroxyethyl)dioctadecylsulfonium, monochloride

Purity: ≥95%

Formula Markup: C38H79OS • Cl

Formula Weight: 619,6

Shelf life (days): 730

Notes: DOSEH is a cationic sulfonium lipid that has been used in the generation of sulfonium lipid nanoparticles (sLNPs) for the delivery of mRNA in vivo.{51948} LNPs containing DOSEH and encapsulating an mRNA reporter accumulate primarily in the lungs after intravenous administration in mice. DOSEH-containing LNPs encapsulating Cre mRNA induce the expression of tdTomato in the lungs of Ai14 mice engineered to express tdTomato upon Cre-mediated recombination.

• SKU: CAY41601-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41601-5
• Package Unit: 5 mg
• Quantity Unit: STK