dsDNA Monoclonal Antibody (Clone 2C4)

dsDNA Monoclonal Antibody (Clone 2C4)
SKU
CAY15635-200
Packaging Unit
1 ea (200 µg)
Manufacturer
Cayman Chemical

Availability: loading...
Price is loading...
Formulation: 200 µg of ammonium sulfate-purified monoclonal antibody

Clone Designation: 2C4

Shelf life (days): 1095

Notes: In response to stimuli, neutrophils have the ability to release net-like structures containing nuclear DNA, de-condensed histones, and antimicrobial peptides.{19770} These neutrophil extracellular traps (NETs) have the ability to contact and kill pathogens including fungi, bacteria, and protozoa; they are then rapidly cleared by the immune system.{24590,24587,25672} However, in aged NZBWF1 mice and human lupus patients, the clearance is delayed, allowing formation of antibodies to these NET components. Cayman’s dsDNA Monoclonal Antibody was developed by fusing the spleen of a non-immunized NZBWF1 mouse with a mouse myeloma cell line. It detects dsDNA by ELISA and can be used to stain NETs by immunofluorescence.
More Information
SKU CAY15635-200
Manufacturer Cayman Chemical
Manufacturer SKU 15635-200
Green Labware No
Package Unit 1 ea (200 µg)
Quantity Unit STK
Clonality Monoclonal
Application Immunofluorescence, ELISA, Flow Cytometry, Immunohistochemistry
Isotype IgM
Host Mouse
Product information (PDF) Download
MSDS (PDF) Download