Abbreviation: DUSP19
Target Synonym: DUSP19;DUSP17;LMWDSP3;SKRP1;TS-DSP1
Conjugation: Unconjugated
UNIProt ID: Q8WTR2
Background: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human DUSP19
Dilution: WB 1:500-1:2000
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