DUSP8 blocking peptide

DUSP8 blocking peptide
SKU
GTX89940-PEP-100
Packaging Unit
100 μg
Manufacturer
GeneTex

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Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89940.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Concentration:

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq, Jul 2008]

Region Sequence: AGDRLPRKVMDAK-C

Full Name: dual specificity phosphatase 8
More Information
SKU GTX89940-PEP-100
Manufacturer GeneTex
Manufacturer SKU GTX89940-PEP-100
Green Labware No
Package Unit 100 μg
Quantity Unit STK
Reactivity Human, Mouse (Murine), Rat (Rattus), Cow (Bovine)
Application ELISA, Blocking, Affinity Purification
Human Gene ID 1850
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