Clone Name: 34C5
Light Chain: Kappa
Application Note: IHC-P: 1:40–1:80. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 427
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
Uniprot ID: P11532
Antigen Species: Human
Immunogen: Prokaryotic recombinant protein corresponding to amino acids 321 to 494 of the dystrophin molecule.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: dystrophin
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