E12CA1A3, CAS 2778182-26-4

Formulation: A solution in ethanol

Formal Name: 2-hexyl-decanoic acid, 2-[4-(dimethylamino)-1-oxobutoxy]dodecyl ester

Purity: ≥98%

Formula Markup: C34H67NO4

Formula Weight: 553,9

Shelf life (days): 365

CAS Number: 2778182-26-4

Notes: E12CA1A3 is an ionizable cationic lipid (pKa = 6.4) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.{72346} LNPs containing E12CA1A3 and encapsulating an mRNA reporter induce luciferase reporter expression in mouse bone marrow-derived dendritic cells (BMDCs) and mice. LNPs containing E12CA1A3 are cleared more rapidly from the liver than LNPs containing DLin-MC3-DMA (Item No. 34364) in mice.

• SKU: CAY40415-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 40415-1
• Package Unit: 1 mg
• Quantity Unit: STK