Product Description: EF-5 (EF5; 2-Nitroimidazole) is a hypoxia labeling agent used to identify hypoxia in cells.
Applications: Cancer-programmed cell death
Formula: C8H7F5N4O3
References: [1]Wang J, et al. The 2-nitroimidazole EF5 is a biomarker for oxidoreductases that activate the bioreductive prodrug CEN-209 under hypoxia. Clin Cancer Res. 2012 Mar 15;18(6):1684-95./[2]Evans SM, et al. Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide]. Br J Cancer. 1995 Oct;72(4):875-82.
CAS Number: 152721-37-4
Molecular Weight: 302.16
Compound Purity: 98.29
Research Area: Cancer
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: Biochemical Assay Reagents