EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), 1mg/mL

EGFRvIII (Epidermal Growth Factor Receptor, Variant III) (GFR/2600R), 1mg/mL
SKU
BTMBNUM2600-50
Packaging Unit
50 uL
Manufacturer
Biotium

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Description: EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Oryctolagus cuniculus (domestic rabbit)

Clone: GFR/2600R

Entrez Gene ID: 1956

Immunogen: KLH conjugate of EGFRvIII-specific, 14-amino acid peptide from the predicted amino acid sequence at the fusion junction (LEEKKGNYVVTDHC)

Verified AB Applications: IHC (FFPE) (verified)

Z-Antibody Applications: IHC, FFPE (verified)
More Information
SKU BTMBNUM2600-50
Manufacturer Biotium
Manufacturer SKU BNUM2600-50
Package Unit 50 uL
Quantity Unit STK
Reactivity Human
Clonality Recombinant
Application Immunohistochemistry
Isotype IgG
Host Rabbit
Conjugate Unconjugated
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