Clone Name: GT1182
Application Note: WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:50 - 1:200. IP: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 36
Form: Liquid
Buffer (with preservative): PBS, 50% Glycerol, 0.02% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]
Uniprot ID: Q15717
Antigen Species: Human
Immunogen: A synthesized peptide derived from human HuR / ELAVL1.
Conjugation: Unconjugated
Full Name: ELAV like RNA binding protein 1
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