Entacapone, CAS 130929-57-6

COMT inhibitor

Product Type: Inhibitor

CAS No.: 130929-57-6

MolecularFormula: C14H15N3O5

Molecular Weight: 305,3

Source: Synthetic

Purity: >98% (HPLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (30 mg/ml); or ethanol (3 mg/ml)

Appearance: Yellow powder

PubChem CID: 5281081

Scientific Background: Entacapone is a selective and reversible inhibitor of the enzyme catechol-O-methyltransferase (COMT). It is used in the therapy of Parkinson's Disease as adjunctive therapy in conjuction with levodopa and carbidopa. It inhibits alpha synuclein and beta-amyloid oligomerization and fibrillogenesis.

References: 1. Di Giovanni S., et al. (2010) J Biol Chem. 285 (20): 14941-14954.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-578-10MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-578-10MG
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK