Formulation: A solid
Formal Name: 4-[1-hydroxy-2-(methyl-d3 amino)ethyl]-1,2-benzenediol
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C9H10D3NO3
Formula Weight: 186,2
Shelf life (days): 1460
CAS Number: 1189977-29-4
Notes: (±)-Epinephrine-d3 is intended for use as an internal standard for the quantification of (±)-epinephrine (Item No. 21245) by GC- or LC-MS. (±)-Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors (Kis = 15, 735, and 3,970 nM for α1A-, β2-, and β1-adrenergic receptors, respectively).{26355,25395,30131} Through these receptors, (±)-epinephrine may induce either contraction or relaxation of vascular smooth muscle, depending on adrenoceptor subtype expression.{30131} Formulations containing (±)-epinephrine have been used in the emergency treatment of severe allergic reactions and the induction and maintenance of mydriasis during intraocular surgery.
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