ESI-05, CAS 5184-64-5

Description: ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.

CAS Number: 5184-64-5

Formula: C16H18O2S

Molecular Weight: 274,38

References: Tsalkova T, et al. Isoform-specific antagonists of exchange proteins directly activated by cAMP. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18613-8.

• SKU: TGMT15247-100mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T15247-100mg
• Package Unit: 100 mg
• Quantity Unit: STK