Clone Name: ESR1/2299R
Application Note: WB: 1-2 μg/ml. IHC-P: 1-2 μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 66
Specificity/Sensitivity: This antibody is specific to ER alpha and shows minimal cross-reaction with other members of the family.
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.
Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
Uniprot ID: P03372
Antigen Species: Human
Immunogen: Recombinant full-length human Estrogen Receptor alpha protein
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: estrogen receptor 1
English
Deutsch
