Products from BPS Bioscience require a minimum order value above 400€
Applications: Useful for the study of EZH2 binding assays, screening inhibitors and selectivity profiling.
Background: EZH2 is a histone methyltransferase that exhibits methylation activity toward H3-K27
Description: The EZH2-EED Binding Assay Kit is designed to measure the inhibition of theprotein-protein interaction between EZH2 and EED. The key to this kit is the specific binding of EZH2 to EED. With this kit, only twosimple steps on a microtiter plate are required. First, incubate a sample containing EZH2, EEDand an inhibitor of choice. Next, incubate with a mixture of acceptor and donor beads, followedby reading the Alpha-counts.
Storage Stability: At least one year from date of receipt when stored as directed.
Supplied As: The kit comes in a convenient AlphaLISA® format, with GST-tagged EZH2, FLAG-tagged EED, and enough assay buffer to perform a total of 384 reactions.
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: Kong, X., et al., J. Med. Chem. 2014; 57:9512.
English
Deutsch
