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Applications: Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Background: FAK (Focal Adhesion Kinase; PTK2) is a protein kinase involving cell adhesion and migration. FAK plays an important role in many cancers including pancreatic tumors. In addition, recent studies showed FAK inhibitor enables an anti-tumor immune response, resulting in tumor destruction in a mouse model.
Description: The FAK Kinase Assay Kit is designed to measure FAK kinase activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.
Storage Stability: Up to 6 months when stored as recommended.
Supplied As: FAK Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant FAK enzyme, FAK substrate, ATP and kinase assay buffer for 100 enzyme reactions.
Biosafety Level: Not applicable (BSL-1)
References: Jiang, H. et al., Nature Medicine 22:851-860 (2016)
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