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Encompassing Amino Acids: 26-762 (end)
Background: FAP expression is seen on activated stromal fibroblasts in >90% ofall human carcinomas, suggesting a role in the development, growth and metastasis ofcarcinomas. It is also involved in the control of wound healing and tissue repair.
Description: Mouse FAP, GenBank Accession No. NM_007986, amino acids 26-762 (end), with C-terminal His-tag, MW=88 kDa, expressed in HEK293 expression system.
Format: Aqueous buffer solution
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: NM_007986
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal His-tag
Uniprot: Q12884
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Edosada,C.Y. et al., J. Biol. Chem. 281 (11), 7437-7444 (2006).
2. Edosada,C.Y. et al., FEBS Lett. 580 (6), 1581-1586 (2006).
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