Abbreviation: FBXO5
Target Synonym: EMI1;FBX5;Fbxo31;FBXO5
Conjugation: Unconjugated
UNIProt ID: Q9UKT4
Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human FBXO5
Dilution: WB 1:500-1:2000
English
Deutsch
