Product Type: Redox Probe
MolecularFormula: C34H37N7O6
Molecular Weight: 639
Source: Synthetic
Solubility: Soluble in DMSO
Appearance: Orange Solid
Scientific Background: FCR1 or flavin coumarin redox sensor 1, is a novel ratiometric fluorescent redox sensor utilized in fluorescence lifetime imaging microscopy and flow cytometry. In the oxidized form, excitation of FCR1 at 405nm results in a green fluorescence with max emissions at 525nm. Treatment with a mild reducing agent (including sodium cyanoborohydride, DTT, and glutathione) reduces the flavin thereby decreasing the green fluorescence intensity, and increasing the blue. Re-oxidation can be achieved using mild oxidizing agents. In general, the FCR1 probe can be used to observe changes in oxidative capacity without interference from background effects.
References: 1. Kaur A., Haghighatbin M.A., Hogan C.F., and New E.J. (2015) Chem. Commun. Epub.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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