Products from BPS Bioscience require a minimum order value above 400€
Encompassing Amino Acids: 400- 821(end), with deletion at 429-430
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Assay Conditions: Assay was done according to BPS Catalog#79502 with a FGFR2 titration range of 0 ng/rxn-500 ng/rxn.
Description: Human FGFR2, also known as Fibroblast growth factor receptor 2, Keratinocyte growth factor receptor, BBDS, BEK, BFR-1 and CD332, GenBank Accession No. NM_000141, a.a. 400-821(end), with deletion at 429-430, with C-terminal His-tag, expressed in an Sf9 infected baculovirus expression system. MW = 52 kDa. This protein was isolated from a co-expression with PTP1B. Percentage of phosphorylation ≤ 10%.
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 100 mM Imidazole, 3 mM DTT and 20% glycerol.
Genbank: NM_000141
Storage Stability: At least 6 months at -80°C.
Supplied As: Aqueous buffer solution.
Tags: C-terminal His-tag
Uniprot: P21802
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Holtrich, U. et al., Proc. Nat. Acad. Sci. (1991); 88:10411-10415.
2. Roidl, A. et al., Clin Cancer Res. (2009 Mar 15); 15(6):2058-66.
English
Deutsch
