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Encompassing Amino Acids: 447-761
Description: Human Fibroblast Growth Factor Receptor 3 (FGFR3), also known as JTK4, and Hydroxyaryl-Protein Kinase with V555F mutation, GenBank Accession No. NM_000142, a.a. 447-761, with N-terminal His-tag, co-expressed with PTP1B for dephosphorylation in an Sf9 cell expression system, phosphorylation level <5%. MW = 37 kDa.
Formulation: 40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 3 mM DTT and 20% glycerol.
Genbank: NM_000142
Purity: >90%
Storage Stability: At least 6 months at -80°C.
Supplied As: Aqueous buffer solution.
Tags: N-terminal His-tag
Uniprot: P22607
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Cappellen, D. et al., Nature Genetics. (1999); 23:18-20.
2. Bellus, G.A. et al., AM. J. Hum. Genet. (1995); 56(2):368-373.