FGFR4 Kinase Assay Kit

Products from BPS Bioscience require a minimum order value above 400€

Applications: Study enzyme kinetics and screen small molecular inhibitors for drug discovery and high throughput (HTS) applications.

Background: FGFR4 (also known as CD334) is a transmembrane receptor with tyrosine kinase activity. The extracellular portion of the receptor contains three immunoglobulin-like domains and is responsible for binding fibroblast growth factor 1 (FGF1). It contains a single transmembrane domain followed by the cytosolic kinase domain. FGFR4 may be involved in ovarian cancer as well as adrenocortical carcinoma and is a promising therapeutic target in oncology applications.  

Contraindications: The final concentration of DMSO in the assay should not exceed 1%.

Description: The Fibroblast growth factor receptor 4 (FGFR4) Kinase Assay Kit is designed to measure FGFR4 kinase activity for screening and profiling applications using ADP-Glo® as a detection reagent. 

Storage Stability: This assay kit will perform optimally for up to 6 months from date of receipt when the materials are stored as directed.

Supplied As: The assay kit comes in a convenient 96-well format, with enough purified recombinant FGFR4 kinase, kinase substrate, ATP and kinase assay buffer for 100 enzyme reactions.

Uniprot: P22455

Warnings: Avoid freeze/thaw cycles

Biosafety Level: Not applicable (BSL-1)

• SKU: BPS78816
• Manufacturer: BPS Bioscience
• Manufacturer SKU: 78816
• Green Labware: No
• Package Unit: 96 rxns.
• Quantity Unit: PAK