Formulation: A solid
Purity: ≥95%
Formula Markup: C35H58O11 (for Filipin III)
Formula Weight: 654,8
Shelf life (days): 1460
CAS Number: 11078-21-0
Notes: Filipin complex is a neutral polyene originally isolated from S. filipinensis with antifungal activity.{42119} It inhibits cell growth as well as mitochondrial terminal electron transport in S. cerevisiae when used at a concentration of 135 µg/ml. Filipin complex binds to various sterols, particularly 24α-methyl cholesterol (Item no. 17344), 24α-ethyl cholesterol (Item no. 11756), and cholesterol, in aqueous solutions and in fungal cell membranes when used at a concentration of 50 µg/ml, inducing membrane pit formation and leakage of cell contents.{42120,9103,42106} It is a fluorescent compound that has been used to label sterols within biological structures for imaging.{9103,8625,42104,42105} Filipin complex displays excitation/emission maxima of 338/480 nm, respectively.
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