Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: FKBP2 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. This gene has two alternatively spliced transcript variants that encode the same isoform. Multiple polyadenylation sites have been described for this gene, but the full length nature of this gene has not been determined.
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FKBP2
Key Reference: Lim,J., (2006) Cell 125 (4), 801-814
Molecular Weight: 16kDa
Peptide Sequence: Synthetic peptide located within the following region:
RLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Peptidyl-prolyl cis-trans isomerase FKBP2
Protein Size: 142
Purification: Affinity Purified
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