Flt3 / CD135(FLT3/2458), 1mg/mL

Flt3 / CD135(FLT3/2458), 1mg/mL
SKU
BTMBNUM2458-50
Packaging Unit
50 uL
Manufacturer
Biotium

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Description: Stem cell tyrosine kinase (STK-1) has been cloned from a CD34 hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of Mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85% identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34 cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The Mouse homolog of STK-1, designated Flt-3/Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: FLT3/2458

Entrez Gene ID: 2322

Immunogen: Recombinant full-length human FLT3 protein

Verified AB Applications: IHC (FFPE) (verified)

Z-Antibody Applications: IHC, FFPE (verified)
More Information
SKU BTMBNUM2458-50
Manufacturer Biotium
Manufacturer SKU BNUM2458-50
Package Unit 50 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Immunohistochemistry
Isotype IgG2b kappa
Host Mouse
Conjugate Unconjugated
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