Formulation: A solid
Formal Name: 2-[[2-(methyl-d3)-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C14H8D3F3N2O2
Formula Weight: 299,3
Shelf life (days): 1460
CAS Number: 1015856-60-6
Notes: Flunixin-d3 is intended for use as an internal standard for the quantification of flunixin (Item No. 26644) by GC- or LC-MS. Flunixin is a non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-1 and COX-2 (IC50s = 3.24 and 0.55 µM, respectively).{48282} It inhibits carrageenan-induced prostaglandin E2 (PGE2; Item No. 14010) and thromboxane B2 (TXB2; Item No. 19030) production in sheep exudate and serum, respectively, when administered at a dose of 1.1 mg/kg.{48283} Flunixin (1.1 mg/L per kg) has anti-inflammatory, analgesic, and antipyretic activity in horses.{48284} Formulations containing flunixin have been used in the veterinary treatment of pain and fever in livestock.
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