FPR2 agonist 2, CAS 2829263-20-7

FPR2 agonist 2, CAS 2829263-20-7
SKU
MEXHY-144604-10
Packaging Unit
10 mg
Manufacturer
MedChemExpress

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Product Description: FPR2 agonist 2 is a potent and permeates the blood?brain barrier FPR2 agonist with an EC50 of 0.13 μM, 1.1 μM for FPR2 and FPR1, respectively. FPR2 agonist 2 inhibits the production of pro-inflammatory cytokines, counterbalances the changes in mitochondrial function, and inhibits caspase-3 activity[1].

Applications: COVID-19-immunoregulation

Formula: C25H20F2N4O2

References: [1]Mastromarino M, et al. Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Ureidopropanamides as Formyl Peptide Receptor 2 (FPR2) Agonists to Target the Resolution of Inflammation in Central Nervous System Disorders. J Med Chem. 2022; 65(6):5004-5028.

CAS Number: 2829263-20-7

Molecular Weight: 446.45

Compound Purity: 99.59

Research Area: Infection; Neurological Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Formyl Peptide Receptor (FPR)
More Information
SKU MEXHY-144604-10
Manufacturer MedChemExpress
Manufacturer SKU HY-144604-10
Package Unit 10 mg
Quantity Unit STK
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