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Encompassing Amino Acids: 33-185
Applications: Useful for binding studies, screening inhibitors, and selectivity profiling.
Description: Secreted frizzled receptor (FZD7)-Fc fusionprotein and WNT receptor, also known asFZD7, GenBank Accession No.BC_015915, a.a. 33-185, expressed in aHEK293 cell expression system. MW = 43.3kDa (monomer). This protein runs at ahigher apparent M.W. by SDS-PAGE due toglycosylation.
Format: Aqueous buffer solution
Formulation: Sterile-filtered (0.2 µm) solution of 40 mM Tris, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: BC_015915
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Fc fusion (Human IgG1)
Uniprot: O75084
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Moffat LL., et al., Development. 2014 Feb;141(3):617-28.2. Surana, R., et al., Biochim Biopys Acta. 2014 Jan;1845(1):53-65.
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