GABA-A Receptor Alpha 2 Antibody, Clone N399/19

Mouse Anti-Rat GABA-A Receptor Alpha2 Monoclonal IgG1

Target: GABA A Receptor

Conjugate: Unconjugated

Product Type: Monoclonal

Clone Number: N399/19 (Formerly sold as S399-19)

Immunogen: Fusion protein amino acids 350-385 (Cytoplasmic C-terminus) of rat GABA-A Receptor Alpha2

Swiss-Prot: P23576

Purification: Protein G Purified

Storage Buffer: PBS pH7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated

Concentration: 1 mg/ml

Specificity: Detects ~55kDa. Does not cross-react with GABA-A Receptor Alpha1.

Cellular Localization: Cytoplasm

Scientific Background: The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2).

References: 1. Bracamontes J.R. and Steinbach J.H. (2008) J Bio Chem. 283: 26128-26136.2. Macdonald R.L., Olsen R.W. (1993) Annu Rev Neurosci. 17: 569-602.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSMC-486D
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SMC-486D
• Green Labware: No
• Package Unit: 100 µg
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Monoclonal
• Application: Immunofluorescence, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotype: IgG1
• Human Gene ID: 289606
• Host: Mouse